Senior Research Associate Job at Flagship Pioneering, Inc.
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
Position Summary:
This is a contract position with a July target start date, running through the end of the year (with potential to extend or convert). The Research Associate I/II will be responsible for developing LNP formulations and processes to support the company's in vitro and in vivo pre-clinical studies. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.
Key Responsibilities:
- Work both independently and as part of a collaborative team to adapt to changing priorities in a fast-paced environment
- Strengthen Tessera's gene editing delivery platforms by developing novel LNPs
- Routinely formulate nucleic acid payloads to support the company's in vitro and pre-clinical studies
- Utilize physicochemical testing methods to screen and characterize novel LNP formulations
- Maintain thorough and detailed electronic lab notebooks and documentation records
- Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies
- Adhere to all laboratory safety requirements and procedures
Basic Qualifications:
- BS/MS in Chemistry, Chemical Engineering, Biomedical Engineering, Material Science, or closely related field with 0-3 years of industrial/academic research experience is required
- Strong communication and collaboration skills
- Highly organized and detail-oriented
- Self-motivated individual who is open to new challenges and has strong scientific rigor
Preferred Qualifications:
- Proven ability to work with a high level of integrity, accuracy, and attention to detail
- Strong organizational skills that enable a high level of productivity and timely completion of assignments
- Excellent oral and written communication skills for effectively interfacing with all members of the company
- Ability to excel in a dynamic, fast-paced, and highly collaborative environment
- Ability to troubleshoot process equipment and analytical instrumentation
- Adapt to changing priorities in a fast-paced environment
- Deliver effectively on time sensitive assignments, and document/communicate scientific data
- Perform experiments that involve preparation and physiochemical characterization of nanoparticles
- Supply LNP test articles for biological studies to enable formulation and process development
- Maintain process and analytical equipment as needed
- Possess a strong work ethic and good documentation practices, including electronic laboratory notebook and inventory maintenance
- Analyze, compile, and present results to internal teams comprised of members from multiple groups and stakeholders
- Perform duties according to applicable safety procedures
- Knowledge of nucleic acid chemistry and biology is a plus
More About Flagship Pioneering
Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
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